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Evaluation of the Susceptibility of Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates to Selected Common Disinfectants | ||
| Veterinary and Comparative Biomedical Research | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 07 مرداد 1404 اصل مقاله (542.35 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.22103/vcbr.2025.25057.1057 | ||
| نویسندگان | ||
| Mina Payan؛ Azizollah Ebrahimi؛ Somayeh Shahrokh Shahraki* | ||
| Department of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran | ||
| چکیده | ||
| Staphylococcus aureus bacteria cause a wide range of infections, from simple skin infections to life-threatening diseases. This bacterium is one of the five most common causes of hospital-acquired infections, particularly post-surgical wound infections. Methicillin-resistant Staphylococcus aureus (MRSA) refers to strains resistant to most antibiotics, predominantly observed in hospitals and currently spreading. Controlling these bacteria necessitates strict management of hospital disinfectants and antiseptics by healthcare personnel. This study evaluates the efficacy of four disinfectants — Cetrimide-C, Vico Science, Intra Hydrocare, and Benzalkonium Chloride — at manufacturer-recommended dilutions on isolated strains of Staphylococcus aureus over different time periods. A standard strain and eight MRSA serotypes were isolated and subjected to verification experiments. Each disinfectant was prepared at the manufacturer's recommended concentration and tested on all nine isolates. The number of viable bacteria was determined by culturing and counting colonies at 5, 10, and 15-minute post-exposure. The results indicated that Cetrimide-C was ineffective at all time intervals. In contrast, Intra Hydrocare, Benzalkonium Chloride, and Vico Science disinfectants were effective at 5, 10, and 15-minute intervals. The efficacy of disinfectants was assessed using the micro-dilution technique. Cetrimide-C at a 1:200 concentration was the least effective disinfectant across all time intervals, while the other three disinfectants were completely effective according to the manufacturer's protocol for all three intervals. | ||
| کلیدواژه‌ها | ||
| Hydrocare Disinfectant؛ Vicosience؛ Cetrimide-C؛ Benzalkonium Chloride؛ Staphylococcus aureus | ||
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آمار تعداد مشاهده مقاله: 5 تعداد دریافت فایل اصل مقاله: 6 |
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