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Polymorphism of pyruvate carboxylase gene and its relation with productive and reproductive performance of dairy cows | ||
Journal of Livestock Science and Technologies | ||
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 24 مرداد 1404 | ||
نوع مقاله: Research Article (Regular Paper) | ||
شناسه دیجیتال (DOI): 10.22103/jlst.2025.25042.1616 | ||
نویسندگان | ||
Waleed Mohammed؛ Haitham Hussein؛ Tahreer Al-Thuwaini* | ||
Department of Animal Production, College of Agriculture, Al-Qasim Green University, Al-Qasim, Babil, Iraq | ||
چکیده | ||
Genetic selection in dairy cattle can be enhanced by identifying the candidate genes and variants associated with economic traits. This study examined the productive and reproductive characteristics of Holstein cattle based on the genotypes of the pyruvate carboxylase (PC) gene. A total of 50 cows, aged three to five years, was included in the study, with identical feeding and maintenance protocols applied to all animals. All cows completed a lactation period of 305 days. The genotype and allele frequencies were determined through genotyping. Sequencing analysis of 816 bp amplicons detected two single-nucleotide polymorphisms (SNPs), rs42195003 and rs110476776. The association analysis of the two SNPs was not significantly associated with lactation period, dry period, milk composition, and reproductive performance (P>0.05). In contrast, the highest milk production (4305.63±222.01 kg), was associated with the CT genotype of the PC (rs110476776) polymorphism. The results revealed that the SNP rs110476776 in the PC gene was associated with total milk production in Holstein cows. This study may provide valuable insights into the role of the analyzed gene in the functional traits of dairy cattle; however, it is essential to validate the results by researching larger populations and different breeds of cattle. | ||
کلیدواژهها | ||
cattle؛ milk traits؛ pyruvate carboxylase؛ polymorphisms؛ reproductive traits | ||
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