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Ghorbanalizadeh, Hassan, Amniattalab, Amir, Neyriz Naghadehi, Moslem. (1404). Renal Amyloidosis in Cattle: An Abattoir-Based Pathological Study in Urmia, Iran. , 2(1), 19-28. doi: 10.22103/vcbr.2025.24452.1030
Hassan Ghorbanalizadeh; Amir Amniattalab; Moslem Neyriz Naghadehi. "Renal Amyloidosis in Cattle: An Abattoir-Based Pathological Study in Urmia, Iran". , 2, 1, 1404, 19-28. doi: 10.22103/vcbr.2025.24452.1030
Ghorbanalizadeh, Hassan, Amniattalab, Amir, Neyriz Naghadehi, Moslem. (1404). 'Renal Amyloidosis in Cattle: An Abattoir-Based Pathological Study in Urmia, Iran', , 2(1), pp. 19-28. doi: 10.22103/vcbr.2025.24452.1030
Ghorbanalizadeh, Hassan, Amniattalab, Amir, Neyriz Naghadehi, Moslem. Renal Amyloidosis in Cattle: An Abattoir-Based Pathological Study in Urmia, Iran. , 1404; 2(1): 19-28. doi: 10.22103/vcbr.2025.24452.1030

Renal Amyloidosis in Cattle: An Abattoir-Based Pathological Study in Urmia, Iran

Veterinary and Comparative Biomedical Research
مقاله 4، دوره 2، شماره 1، شهریور 2025، صفحه 19-28    اصل مقاله (1.86 M)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22103/vcbr.2025.24452.1030
نویسندگان
Hassan Ghorbanalizadeh1؛ Amir Amniattalab* 2؛ Moslem Neyriz Naghadehi3
1Faculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran
2Department of Pathology, Faculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran
3Department of Food Hygiene, Faculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran
چکیده
Serum-associated amyloidosis is the most common form of amyloidosis in domestic animals and can lead to death. In this study, 1294 cattle (with a total of 2588 kidneys inspected) were inspected at the Sahand Abattoir, Urmia, Iran, over one year. Of these, 2462 kidneys were healthy (95.1%) while 126 kidneys had lesions (4.9%). There was no significant correlation between the frequency of gross lesions in the kidney and the sex or breed of the cattle (p>0.05). Additionally, the frequency of macroscopic changes in all cattle aged 4.5 years and older was significantly higher than that of younger ones and calves (p<0.05). Microscopic examination using hematoxylin and eosin, periodic acid schiff, and congo red tissue staining methods revealed the relative frequency of kidney lesions as follows: hemorrhage (27%), hydropic degeneration (16.7%), congestion (15.9%), interstitial nephritis (8.7%), glomerulonephritis (7.1%), acute tubular necrosis (6.3%), hydronephrosis (4.8%), cysts (4%), fibrosis (3.2%), amyloidosis (1.6%), pyelitis (1.6%), and renal lipidosis (0.8%). In two kidneys with amyloid deposits, one belonged to a bull with localized pulmonary tuberculosis, while the other belonged to a different bull with no other lesions detected in any organs. The most involved structures were glomeruli (98%), and only 2% of cortical tubules had amyloid deposits. Although renal amyloidosis is rare in slaughtered cattle in Urmia city, its heat resistance and potential transmission through food, especially to individuals with chronic inflammatory diseases, require careful inspection in slaughterhouses and condemnation of suspicious carcasses.
کلیدواژه‌ها
Renal amyloidosis؛ Cattle؛ Tissue lesions؛ Abattoir
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